Risks of skin depigmentation


Vitiligo can sometimes be a sign of serious problems, such as:

  • Addison’s disease
  • excessive activity of the immune system
  • type I diabetes

Vitiligo, as well as hypopigmentation of the skin caused by fungal infestation, does not cause serious damage to health, but it can still generate psychological discomfort in the patient and make him feel “sick” or socially “little accepted”.

However, the white spots on the skin are more exposed to sunburn and erythema, following exposure to the sun, precisely because of the lack of melanin that characterizes these areas.

Areas most affected by skin depigmentation

Skin depigmentation caused by vitiligo generally occurs on the periungual area and in areas of the body near “openings” (eyes, genitals, anus); however, white spots may also develop on the legs, hands and neck.

When the spots are caused by a fungal infection, they appear preferably on the trunk, along the back and on the neck.

Skin depigmentation treatment

Treatment of vitiligo generally aims to reactivate the activity of melanocytes; to this end, ultraviolet rays can be applied to the affected areas in the clinic, sometimes combined with photosensitizing substances.

The treatment of white spots caused by Pityriasis versicolor instead involves the administration of antifungals by the dermatologist.In both cases the white spots can persist and hardly regress, creating an aesthetic damage to the patient.

What if it’s vitiligo? Listen to our podcast

In the Vitiligo podcast, two patients tell their relationship with the appearance of white spots on their body. Click here to listen to it.

  • Pigmentation of the skin of the face
  • possible causes and remedies
  • duration time 3 minutes of reading

Facial skin depigmentation and pigmentation can occur suddenly for no apparent reason or can be caused by hormonal imbalances and photo-aging. Here is everything you need to know about facial depigmentation and pigmentation and above all what the treatments and remedies to counteract this annoying blemish.

Facial depigmentation


Facial depigmentation is the loss of melanocytes with the formation of lighter spots on the skin. One of the most common disorders of skin pigmentation is vitiligo, which causes the appearance of lighter areas and can occur anywhere on the body.

Facial depigmentationIn other cases, the depigmentation can be triggered by fungi or other systemic conditions. These can be temporary or permanent conditions such as in the case of vitiligo. In skin areas where depigmentation occurs, melanocytes no longer produce sufficient quantities of melanin, which causes the formation of lighter areas of the skin.



On the other hand, skin pigmentation is much more widespread because it involves everyone. Over time, in fact, age spots intensify especially on the face and hands, the parts most exposed to the sun. In fact, one of the main causes of pigmented spots on the skin is exposure to the sun.

In addition, moreover, in periods of particular hormonal imbalance, these pigmented spots on the skin intensify in women. This is the case of melasma or pregnancy mask which can affect pregnant women. In these cases it is the reverse process of skin depigmentation: the melanocytes produce more melanin thus generating darker areas of the skin.

The pigmentation of the skin of the face, therefore, can be caused by 3 different factors:

● Sun rays and pollution. This combination produces free radicals which cause oxidative stress and pigmentation problems of the facial skin;

● Acne-prone skin marks leave dark, thickened areas on the skin; those with this type of skin may have dark spots on the face, as well as tattoos can generate redness and consequent hyperpigmentation;

● Hormonal impairment.


Face pigmentation, therefore, can be triggered by premature photo-aging, by the action of sunlight combined with that of polluting particles, by acne-prone skin,Pigmentclar is the line designed by La Roche-Posay Laboratories to treat facial pigmentation and the formation of skin spots. Dermocosmetic products suitable for treating spots and dull complexion due to exposure to UVA and UVB rays, pollution or acne-prone skin.

In particular, Pigmentclar UV SPF 30 cream protects against environmental aggression, including polluting particles because it counteracts their adhesion to the skin, and from UVA and UVB rays thanks to the innovative SPF 30 and PPD 15 filter system.

Counteracts oxidative stress thanks to the action of the formula enriched with ginkgo and ferulic acid which help protect the skin from free radicals triggered by external factors. The result? The skin will be more homogeneous and luminous.